NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Cucurbitacin I

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

Janus kinase 2

Breast Carcinoma

MDA-MB-435

0.18±0.07 µM

-

-

-

Cucurbitacin I treatment suppressed P-JAK2.

Janus kinase 2

Lung adenocarcinoma

A549

0.25±0.09 µM

-

-

-

Cucurbitacin I treatment suppressed P-JAK2.

Janus kinase 2

Breast Carcinoma

MDA-MB-468

0.40±0.26 µM

-

-

-

Cucurbitacin I treatment suppressed P-JAK2.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.