NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Cucurbitacin B

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CCNB1cyclin B1891Epidermoid carcinoma of larynxHep-2----Measuring the modulation of regulators in the cell cycle, apoptosis and signal transductions by Western blot analysis showed that the effect of cucurbitacin B was due to suppression of the expression of cyclin B1.18309509
CCNB1cyclin B1891Pancreatic CancerPANC-1----The cell cycle regulators cyclin B1 decreased after 24 h exposure to cucurbitacin .19605406

 






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