NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Cucurbitacin A

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
JAK2Janus kinase 23717Lung adenocarcinomaA5491.5±0.7 µM---Cuc A suppressed the levels of P-JAK2 in A549 cells.15735720
JAK2Janus kinase 23717Breast CarcinomaMDA-MB-4530.65±0.05 µM---Cucurbitacin A suppressed the levels of P-JAK.15735720
JAK2Janus kinase 23717Breast CarcinomaMDA-MB-4680.86 µM---Cucurbitacin A suppressed the levels of P-JAK.15735720

 






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