NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: cryptolepine

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

caspase 3, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

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-

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The caspase-3-mediated cleavage activity stimulated by cryptolepine was totally inhibited by the inhibitor z-DEVD-fmk data not shown. The results suggest that cryptolepine activates caspase-3.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.