NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Butein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Human promyelocytic leukemiaHL-60----The treatment of the cells with butein increased the caspase-3 activity11393587
CASP3caspase 3, apoptosis-related cysteine peptidase836Prostate CancerLNCaP----Treatment of LNCaP cells with butein (10-30 µM) caused an increase in the activation of caspases-3, -8, and -9 dose dependently.22114764

 






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