NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Bisabolol

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP8caspase 8, apoptosis-related cysteine peptidase841HepatomaHep G2----the active form of caspases-8 and -9 was observed rather earlier than caspase-3, which suggested that caspase-8 may functions as an upstream regulator in a-bisabolol-induced apoptosi.20346922
FasTNF receptor superfamily, member 6355HepatomaHep G2----bisabolol strongly increased the expression of Fas. It was also observed that the activation of Fas was much earlier than that of p53 and NF-kappaB.20346922
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790HepatomaHep G2----bisabolol strongly increased the expression of NF-kappaB, 20346922
TP53tumor protein p537157HepatomaHep G2----bisabolol strongly increased the expression of p5320346922

 






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