NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Betulinic acid

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

baculoviral IAP repeat-containing 5a

Prostate Cancer

LNCaP

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Betulinic acid also induced caspase-dependent PARP cleavage in LNCaP cells, and this was accompanied by decreased expression of the antiapoptotic protein survivin and induction of DNA laddering typically observed in cells undergoing apoptosis.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.