NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Betulinic acid

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
BCL2B-cell CLL/lymphoma 2596Breast CarcinomaT-47D----Tumor cell lines showed a decrease of bcl-2 expression when incubated with 1 µM or 5 µM betulinic acid for 24 h.16964520
BCL2B-cell CLL/lymphoma 2596MedulloblastomaTE-671----Tumor cell lines showed a decrease of bcl-2 expression when incubated with 1 µM or 5 µM betulinic acid for 24 h.16964520
BCL2B-cell CLL/lymphoma 2596Multiple MyelomaRPMI-8226----Tumor cell lines showed a decrease of bcl-2 expression when incubated with 1 µM or 5 µM betulinic acid for 24 h.16964520
BCL2B-cell CLL/lymphoma 2596Neuroblastoma SK-N-AS----Tumor cell lines showed a decrease of bcl-2 expression when incubated with 1 µM or 5 µM betulinic acid for 24 h.16964520
BCL2B-cell CLL/lymphoma 2596T cell leukemiaJurkat E6.1----Tumor cell lines showed a decrease of bcl-2 expression when incubated with 1 µM or 5 µM betulinic acid for 24 h.16964520
BCL2B-cell CLL/lymphoma 2596Thyroid carcinomaFTC238----Tumor cell lines showed a decrease of bcl-2 expression when incubated with 1 µM or 5 µM betulinic acid for 24 h.16964520

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.