NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Beta-lapachone

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 14790LeukemiaU-937----Although NF-kB was activated intensely by 10,000 pM TNF, beta-lapachone inhibited the activation as completely as it did at the 0.1 nM concentration. These results show that beta-lapachone is a very potent inhibitor of NF-kB activation.10075082

 






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