NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: Beta-Lapachone

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

cyclin B1

Colon cancer

SW-620

-

-

-

-

Cyclin B1 expression was prominently up-regulated, a finding consistent with the late S-and G2/M-phase arrest induced by ,B-lapachone at 24 hr post-treatment.

cyclin B1

Colon Adenocarcinoma

DLD-1

-

-

-

-

Cyclin B1 was prominently down-regulated, which is consistent with the early S-phase arrest induced by beta-lapachone at 24 hr post-treatment.

cyclin B1

Colon Cancer

SW-480

-

-

-

-

In SW480 cells,the expression of the G2 /M phase-specific cyclin B1 was prominently down-regulated

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.