NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Beta-Ionone

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Human osteosarcomaU2os----The Caspase-3 cellular activity showed a significant increase in cells treated with 200 lM b-ionone for 48 h compared with cells treated with b-ionone for 12 or 24 h. Because the activity of Caspase-3 was significantly increased in U2os cells treated with 200 lM b-ionone for 48 h, this treatment was considered to represent the optimal induction condition of apoptosis.19757179

 






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