Compound: Berbamine

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

birc5a

baculoviral IAP repeat-containing 5a

Leukemia

K-562

berbamine significantly down-regulated Survivin and the ratio of Survivn/b-actin decreased.

conserved helix-loop-helix ubiquitous kinase

Leukemia

K-562

After 24 hr of treatment, berbamine significantly inhibited the expression of IKK-alpha.

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Leukemia

K-562

the levels of nuclear FjB(p65) were down-regulate.

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha

Leukemia

K-562

After 24 hr of treatment, berbamine significantly inhibited the expression of phospho-I-kappa-B-alpha.

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase