NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Baicalein

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Human promyelocytic leukemiaHL-60----Baicalein induced HL-60 apoptosis via promoted caspase-3 pathway.The results indicate that activation of caspase 3 contributes to baicalein-induced apoptosis.14630128
CASP3caspase 3, apoptosis-related cysteine peptidase836Lung CancerH-460----Proform of caspase-3 was sig-nificantly decreased after treatment with 50 lM baicaleinfor 4 .17050058
CASP3caspase 3, apoptosis-related cysteine peptidase836Lung squamous CarcinomaCH27----The expression of Caspase-3 proform were significantly decreased after treatment with baicalein for 8 h.15868934

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.