| CYPIA1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | 1543 | Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virus | RAW264.7 | 0.02 µM | - | - | - | Apigenin potently inhibited Cyp1A activity with an IC50 of 0.02 µM Cyp1A, which is e.g. involved in the activation of carcinogens from grilled meat, as a model phase 1 enzyme, and measured the potential of beer constituents to inhibit its enzymatic activity. | Phytochemistry Reviews 1: 369-377, 2002 |