NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Apigenin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDK1cyclin-dependent kinase 1983Human MelanomaOCM-1----Apigenin inhibited CDK-1 in OCM-1 cell line.11322924
CDK1cyclin-dependent kinase 1983Colon CancerHT-29----p34cdc2 kinase activity was significantly reduced by apigenin, at least in the high concentrations of 50-80 mM, for 24 h in each of three cell lines in comparison with the vehicle controls10900467
CDK1cyclin-dependent kinase 1983Colon CancerSW-480----p34cdc2 kinase activity was significantly reduced by apigenin, at least in the high concentrations of 50-80 mM, for 24 h in each of three cell lines in comparison with the vehicle controls10900467
CDK1cyclin-dependent kinase 1983Colorectal AdenocarcinomaCaCo-2----p34cdc2 kinase activity was significantly reduced by apigenin, at least in the high concentrations of 50-80 mM, for 24 h in each of three cell lines in comparison with the vehicle controls10900467

 






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