| CDK4 | cyclin-dependent kinase 4 | 1019 | Breast Carcinoma | MDA-MB-231 | - | - | - | - | Real-time analysis revealed that the expression of p21cip1 was up-regulated and CHEK2 expression tended to increase for more than 6 h after alpha-mangostin treatment. p21cip1 is a cyclin dependent kinase inhibitor and the encoded protein binds to and inhibits the activity of cyclin-CDK2 (CDK: cyclindependent kinase. | 22577295 |