NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Acteoside

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CDK2cyclin-dependent kinase 21017Human promyelocytic leukemiaHL-60----The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to decreases in the CDK217634406
CDK4cyclin-dependent kinase 41019Human promyelocytic leukemiaHL-60----The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to decreases in the CDK417634406
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)1026Human promyelocytic leukemiaHL-60----The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to up-regulation of the p21CIP1/WAF117634406
CDKN1Bcyclin-dependent kinase inhibitor 1B (p27, Kip1)1027Human promyelocytic leukemiaHL-60----The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to up-regulation of the p27KIP1 levels 17634406

 






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