NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Acteoside

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

cyclin-dependent kinase 2

Human promyelocytic leukemia

HL-60

-

-

-

-

The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to decreases in the CDK2

cyclin-dependent kinase 4

Human promyelocytic leukemia

HL-60

-

-

-

-

The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to decreases in the CDK4

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

Human promyelocytic leukemia

HL-60

-

-

-

-

The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to up-regulation of the p21CIP1/WAF1

cyclin-dependent kinase inhibitor 1B (p27, Kip1)

Human promyelocytic leukemia

HL-60

-

-

-

-

The onset of acteoside-induced G1 arrest of HL-60 cells prior to the differentiation appears to be tightly linked to up-regulation of the p27KIP1 levels

Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.