NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

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Compound: 2-alpha-Hydroxyursolic acid

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

Breast adenocarcinoma

MCF-7

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Results suggest that 2-alpha-hydroxyursolic acid has antiproliferative activities against MCF-7 cells and capabilities inhibiting NF-kappaB activation induced by TNF-alpha partially by suppressing proteasome activities.

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Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.