Compound: 28-deoxonimbolide

Targets

Gene Name

Gene ID

Cancer

Cell Lines

IC₅₀

ED₅₀

EC₅₀

GI₅₀

Remark

References

CASP3

caspase 3, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

The levels of procaspase-3 diminished, and then the levels of cleaved caspases-3 were increased after treatment with compound.

caspase 8, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

The levels of procaspase-8 diminished, and then the levels of cleaved caspases-8 were increased after treatment with compound.

caspase 9, apoptosis-related cysteine peptidase

Human promyelocytic leukemia

HL-60

The levels of procaspase-9 diminished, and then the levels of cleaved caspases-9 were increased after treatment with compound.

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase