NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: 28-deoxonimbolide

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
CASP3caspase 3, apoptosis-related cysteine peptidase836Human promyelocytic leukemiaHL-60----The levels of procaspase-3 diminished, and then the levels of cleaved caspases-3 were increased after treatment with compound.21381696
CASP8caspase 8, apoptosis-related cysteine peptidase841Human promyelocytic leukemiaHL-60----The levels of procaspase-8 diminished, and then the levels of cleaved caspases-8 were increased after treatment with compound.21381696
CASP9caspase 9, apoptosis-related cysteine peptidase842Human promyelocytic leukemiaHL-60----The levels of procaspase-9 diminished, and then the levels of cleaved caspases-9 were increased after treatment with compound.21381696

 






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