NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: (-)-Epicatechin

TargetsGene NameGene IDCancerCell LinesIC50ED50EC50GI50RemarkReferences
COX-1cytochrome c oxidase subunit I4512Murine monocyte/macrophage line derived from ascitic tumour induced with Abelson leukaemai virusRAW264.77.5 µM---It inhibits cyclooxygenase 1 (Cox-1) activity and it is an anti-inflammatory mechanism.Phytochemistry Reviews 1: 369-377, 2002
COX-1cytochrome c oxidase subunit I4512--3.2 µM---Testing of compound was performed in-vivo. Compound is shown have anticancer activity.11962253

 






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