NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: 2-alpha, 3-alpha, 19-beta, 23-beta-tetrahydroxyurs-12-en-28-oic acid

ModelsTargetInhibitory ConcRemarkReference
A2780 ovary tumor growth in nude mice--Tested compound (at doses of 25 and 50 mg/kg) resulted in 39% (P<0.01) and 61% (P<0.001) tumor growth inhibition (compared to control mice treated with saline) in the A2780 xenograft tumor model. Within the "non-toxic’’ range, THA exhibited a significant antitumor activity to xenograft tumors derived from the A2780 ovarian cancer cell line21695177

 






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