NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Silvestrol

ModelsTargetInhibitory ConcRemarkReference
MDA-MB-231 breast cancer xenografts--At 11 days after implantation, silvestrol was administered intraperitonally at 0.5 mg/kg once per day for 8 consecutive days. It was noted that silvestrol dramatically suppressed the growth of these tumors19401772
PC-3 xenografts--Growth of PC-3 xenografts was significantly reduced in mice dosed with 0.5 mg/kg silvestrol for 8 consecutive injections following appearance of the tumors 24 days after implantation19401772

 






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