NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Sanguinarine

ModelsTargetInhibitory ConcRemarkReference
DU145 xenograft modelSurvivin-The tumor growth in sanguinarine-treated group was suppressed starting at 31 days post cell inoculation and throughout the treatment period until 56 days when the mice were sacrificed . The levels of survivin protein expression in tumors were decreased in sanguinarine treatment group compared to the control group. These data demonstrated that sanguinarine was able to suppress the tumor growth of DU145 human prostate cancer cells.21318089

 






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