NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Resveratrol

ModelsTargetInhibitory ConcRemarkReference
LNCaP cancer cell xenografts in athymic nude mice--In a xenograft model, resveratrol delayed LNCaP tumor growth and inhibited expression of a marker for steroid hormone responses. However, exposure to resveratrol also led to increased angiogenesis and inhibition of apoptosis in the xenograft.CARCIN-2007
NGP xenograft model--Mice were treated daily with resveratrol doses of 2, 10, and 50 mg/kg. After nearly 5 weeks of oral drug treatment, tumor growth was most strongly inhibited at the highest dose17785572
SK-N-AS xenograft model--After 5 weeks of oral drug treatment,Tumor volume was nearly 80% less than that in the vehicle-treated and untreated control groups (P= 0.0003 and 0.0006, respectively).17785572

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.