NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Naringenin

ModelsTargetInhibitory ConcRemarkReference
Lewis lung carcinoma injected C57Bl/6 female mice model--Tumor growth in mice treated with doxorubicin in combination with naringenin was dramatically decreased after oral administration of naringenin for 3 weeks, compared to mice treated doxorubicin alone. The mice that were given doxorubicin alone showed a decrease in body weight. In contrast, mice treated with the same dose of doxorubicin combined with naringenin began to gain weight at the start of treatment and attained body weight equal to that of control on day 35 (P>0.05). The results demonstrate that naringenin might synergistically enhance the antitumor effect of doxorubicin19067124

 






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