NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Lupeol

ModelsTargetInhibitory ConcRemarkReference
HCC tumor model was established by injecting MHCC-LM3 cells in BALB/c-nu/nu 4-to 6-week-old male athymic nude mice--Lupeol dramatically decreased the tumor volumes of MHCC-LM3 HCC cell line-derived xenografts, and the effect was equivalent to that of combined cisplatin and doxorubicin treatment. Lupeol exerted a synergistic effect without any adverse effects on body weight when combined with chemotherapeutic drugs.20979057

 






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