NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Hesperetin

ModelsTargetInhibitory ConcRemarkReference
Athymic mice were ovariectomized and transplanted with aromatase-overexpressing MCF-7 cellspS2-Dietary administration of Hesperetin(HSP) at 1000 ppm and 5000 ppm significantly deterred the xenograft growth. Dietary HSP treatment significantly (P<.05) inhibited pS2 expression induced by the exogenous androstenedione.22209285
Athymic mice were ovariectomized and transplanted with aromatase-overexpressing MCF-7 cellsCYP1A1-CYP1A1 expression was significantly induced by androstenedione administration, and cotreatment with HSP repressed the increase22209285

 






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