| azoxymethane (AOM)-induced colon carcinogenesis in F344 rats | Glutathione S-transferase(GST) | - | GST activity in the liver was signifcantly elevated by gavage of FA at a dose of 100 mg/kg body weight (P< 0.03). It significantly increased the activities of detoxification enzymes GST and QR in the liver and/or colonic mucosa. Thus, such evidence for the activity on the detoxifying enzymes may also be related to the blocking effect of FA on AOM-induced colon carcinogenesis. | 10893437 |