NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: Acacetin

ModelsTargetInhibitory ConcRemarkReference
OVCAR-3 cells were implanted on chicken chorioallantoic membrane (CAM)VEGF-Acacetin treatment inhibited tumor growth with 50% decrease of tumor weight when compared to that from the control group, indicating that acacetin suppresses tumor growth through impeding the angiogenesis. Acacetin inhibited the levels of VEGF expression in tumor tissue samples21893035
OVCAR-3 cells were implanted on chicken chorioallantoic membrane (CAM)HIF-1ALPHA-The micro-vessel density was decreased by acacetin treatment to 50% of the control,showing that acacetin inhibited ovarian cancer cells-induced angiogenesis in vivo. Acacetin inhibited the levels of HIF-1alpha in tumor tissue samples21893035

 






Copyright © 2012. Subhash M. Agagrwal. All Rights Reserved.