NPACT- Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase

Compound: (-)-Gossypol

ModelsTargetInhibitory ConcRemarkReference
xenografts using the UM-SCC-17B and UM-SCC-1 cell lines.--In both 5 and 15 mg/kg (-)-gossypol treatment groups, a significant suppressive effect on tumor growth was observed. By day 28, control animals had, on average, tumors that are 253 mm3 (SE = 95,P= .008) and 268 mm3 (SE = 95, P= .006) larger than those in animals treated with 5 and 15 mg/kg ( )-gossypol, respectively.16611409

 






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