Compound	Hyperforin
NPACT-Id	NPACT00667
IUPAC	(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
Synonyms	hiperforina;hyperforine
PubChem Id	441298
Class	Terpenoids
In-vitro anticancer activity	10 cancer cell lines
In-Vivo anticancer activity	Yes
Targets	AKT1 \| CASP3 \| CASP9 \| All \|
Properties	Physical Elemental Topological
InChi Key	KGSZHKRKHXOAMG-HQKKAZOISA-N
InChi	1S/C35H52O4/c1-22(2)13-12-19-33(11)27(16-14-23(3)4)21-34(20-18-25(7)8)30(37)28(17-15-24(5)6)31(38)35(33,32(34)39)29(36)26(9)10/h13-15,18,26-27,37H,12,16-17,19-21H2,1-11H3/t27-,33+,34+,35-/m0/s1
SMILES	O=C1[C@]2([C@@]([C@H](C[C@@]1(C(=C(C2=O)CC=C(C)C)O)CC=C(C)C)CC=C(C)C)(CCC=C(C)C)C)C(=O)C(C)C
SMART	[H]OC1=C(C(=O)[C@@]2(C(=O)[C@]([H])(C([H])([H])[H])C([H])([H])[H])C(=O)[C@]1(C([H])([H])C([H])=C(/C([H])([H])[H])C([H])([H])[H])C([H])([H])[C@]([H])(C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])[C@@]2(C([H])([H])[H])C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H])C([H])([H])C([H])=C(/C([H])([H])[H])C([H])([H])[H]
CAS No.	11079-53-1
Structure Download
Cross Refrence in other databases
	Super Natural	011079531
	CTD	C001654
	HIT	C0275
	NCI-60 GI₅₀ data	-
Suppliers	Ambinter, Calbiochem,
Drug-Likeliness Filters	Lipinski's rule of five	No
	Ghose filter	No
	Veber filter	No
	Muegge Filter	No
Similarity Search	Human metabolite database	FDA approved drugs

NPACT

Naturally occuring Plant based Anticancerous Compound-Activity-Target DataBase