Primary information |
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ID | 1523 |
Peptide Name | Peptide 131-151 P140 |
Sequence | RIHMVYSKRS(P)GKPRGYAFIEY |
Length | 21 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | phosphorylation at Ser140 |
Linear/ Cyclic | Linear |
Nature | Protein Derived |
Source of Origin | Spliceosomal U1-70K protein |
Target | HLA class II molecules |
Mechanism of Action | IL-10 secretion |
In vitro/In vivo | In vivo |
Cell Line | NA |
Inhibition Concentartion | NA |
In vivo Model | MRL/lpr mice |
Assay | HLA-DR peptide-binding assay, ELISA, CFSE, PBMC Proliferation assay |
Lethal Dose | NA |
Combination Therapy | lupus |
Pubmed ID | 16237076 |
Year of Publication | 2005 |
3-D Structure | View in Jmol or Download Structure |