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1522 details |
| Primary information | |
|---|---|
| ID | 1522 |
| Peptide Name | Peptide 131-151 |
| Sequence | RIHMVYSKRSGKPRGYAFIEY |
| Length | 21 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Protein Derived |
| Source of Origin | Spliceosomal U1-70K protein |
| Target | HLA class II molecules |
| Mechanism of Action | IL-10 secretion |
| In vitro/In vivo | In vivo |
| Cell Line | NA |
| Inhibition Concentartion | NA |
| In vivo Model | MRL/lpr mice |
| Assay | HLA-DR peptide-binding assay, ELISA, CFSE, PBMC Proliferation assay |
| Lethal Dose | NA |
| Combination Therapy | lupus |
| Pubmed ID | 16237076 |
| Year of Publication | 2005 |
| 3-D Structure |  View in Jmol or Download Structure |