Primary information |
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ID | 1435 |
Peptide Name | Nef2-19 |
Sequence | GGKWSKSSVIGWPAVRERMRR |
Length | 21 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Natural |
Source of Origin | NL4.3 strain of HIV-1 |
Target | T -cells |
Mechanism of Action | Downregulates CD4 and IL-2 |
In vitro/In vivo | In vitro |
Cell Line | CD4+ T-cell lines, PBMC, MT-2 cells, Jurkat cells |
Inhibition Concentartion | NA |
In vivo Model | None |
Assay | Hummoral Immune Response assay |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | US 6197583 B1 |
Year of Publication | 2001 |
3-D Structure | View in Jmol or Download Structure |