| Primary information |
|---|
| ID | 1435 |
| Peptide Name | Nef2-19 |
| Sequence | GGKWSKSSVIGWPAVRERMRR |
| Length | 21 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Linear |
| Nature | Natural |
| Source of Origin | NL4.3 strain of HIV-1 |
| Target | T -cells |
| Mechanism of Action | Downregulates CD4 and IL-2 |
| In vitro/In vivo | In vitro |
| Cell Line | CD4+ T-cell lines, PBMC, MT-2 cells, Jurkat cells |
| Inhibition Concentartion | NA |
| In vivo Model | None |
| Assay | Hummoral Immune Response assay |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | US 6197583 B1 |
| Year of Publication | 2001 |
| 3-D Structure |  View in Jmol or Download Structure |
