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1112 details |
| Primary information | |
|---|---|
| ID | 1112 |
| Peptide Name | Antamides |
| Sequence | VPPAFFPPFF |
| Length | 10 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Cyclic |
| Nature | Natural |
| Source of Origin | Amanita phalloides spp. (fungus) |
| Target | NA |
| Mechanism of Action | Inhibition of mitochondrial permeability transition pores |
| In vitro/In vivo | Both |
| Cell Line | fibroblasts |
| Inhibition Concentartion | NA |
| In vivo Model | C57BL/6 mice |
| Assay | NA |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | 24333193 |
| Year of Publication | 2014 |
| 3-D Structure | NA |