Detailed description page of ImmunoSPdb

This page displays user query in tabular form.

1091 details
Primary information
ID1091
Peptide NameTransforming growth factor beta 1 (TGFβ1)
Sequencenot available
Length0
ChiralityL
N-terminal ModificationNone
C-terminal ModificationNone
Chemical ModificationNone
Linear/ CyclicLinear
NatureProtein Derived
Source of OriginHuman melanoma cell line
TargetIL-7
Mechanism of ActionThe immunosuppressive peptide TGFβ1 was inhibited in a human melanoma cell line transduced with IL-7
In vitro/In vivoBoth
Cell LineM- 14 and M-24
Inhibition ConcentartionNA
In vivo ModelCongenitally athymic (nu/nu) BALB/c mice
AssayTGFβ1 bioassay
Lethal DoseNA
Combination TherapyNA
Pubmed ID8260705
Year of Publication1993
3-D StructureNA