Primary information |
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ID | 1065 |
Peptide Name | Cyclolinopeptide A (CLA) |
Sequence | VPPFFLIIL |
Length | 9 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Cyclic |
Nature | Synthetic |
Source of Origin | NA |
Target | NA |
Mechanism of Action | Inhibition of the action of interleukin-1 and interleukin-2 |
In vitro/In vivo | Both |
Cell Line | SRBC (sheep red blood cells) |
Inhibition Concentartion | NA |
In vivo Model | CBA/Iiw mice 8-10 weeks |
Assay | Humoral immune response test,PFC (plaque froming cell) test, DTH (delayed type hypersensitivity) test |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | 8441706 |
Year of Publication | 1992 |
3-D Structure | View in Jmol or Download Structure |