| Primary information |
|---|
| ID | 1064 |
| Peptide Name | Antamanide |
| Sequence | VPPAFFPPFF |
| Length | 10 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | None |
| Linear/ Cyclic | Cyclic |
| Nature | Natural |
| Source of Origin | Isolated from the poisonous mushroom Amanita phalloides |
| Target | Peptidyl-prolyl cis-trans isomerase CyP-D |
| Mechanism of Action | Inhibit mitochondrial permeability transition pore |
| In vitro/In vivo | Both |
| Cell Line | HeLa Cells |
| Inhibition Concentartion | NA |
| In vivo Model | C57BL/6 mice |
| Assay | Cell Viability assay, Ca2+ retention capacity assay |
| Lethal Dose | NA |
| Combination Therapy | NA |
| Pubmed ID | 21297983 |
| Year of Publication | 2011 |
| 3-D Structure |  View in Jmol or Download Structure |
