| Primary information |
|---|
| ID | 1063 |
| Peptide Name | Kalata B1 |
| Sequence | GLPVCGETCVGGTCNTPGCTCSWPVCTRN |
| Length | 29 |
| Chirality | L |
| N-terminal Modification | None |
| C-terminal Modification | None |
| Chemical Modification | Three cystine knot Disulfide connectivity (CI-CIV, CII-CV and CIII-CVI) |
| Linear/ Cyclic | Cyclic |
| Nature | Natural |
| Source of Origin | From Oldenlandia affinis Plant Extract |
| Target | NA |
| Mechanism of Action | Inhibits the growth of the Lymphocytes in a cytostatic fashion |
| In vitro/In vivo | In vitro |
| Cell Line | Human Peripheral Blood Mononuclear Cells |
| Inhibition Concentartion | 3.9±0.5 micromolar for antiproliferative effect on PBMC |
| In vivo Model | NA |
| Assay | Cell Proliferation assay, Cell division assay |
| Lethal Dose | 14 micromolar of the peptide are cytotoxic to the cells |
| Combination Therapy | NA |
| Pubmed ID | 22272797 |
| Year of Publication | 2012 |
| 3-D Structure | NA |
