Primary information |
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ID | 1062 |
Peptide Name | Charybdotoxin (ChTX) |
Sequence | EFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS |
Length | 37 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Natural |
Source of Origin | Venom of the scorpion Leiurusquin questriatus var. hebraeus |
Target | K+ channels |
Mechanism of Action | Potent selective block of apamin-insensitive Ca2+- activated K+ channels |
In vitro/In vivo | In vitro |
Cell Line | GH3 pitutary cells and aortic smooth muscle |
Inhibition Concentartion | NA |
In vivo Model | NA |
Assay | NA |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | 2453055 |
Year of Publication | 1988 |
3-D Structure | View in Jmol or Download Structure |