Primary information |
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ID | 1052 |
Peptide Name | Margatoxin |
Sequence | TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH |
Length | 39 |
Chirality | L |
N-terminal Modification | None |
C-terminal Modification | None |
Chemical Modification | None |
Linear/ Cyclic | Linear |
Nature | Natural |
Source of Origin | Purified from venom of the scorpion Centruroides margaritatus |
Target | Kv1.3 channel |
Mechanism of Action | Inhibit both Th1 and Th2 cytokine production |
In vitro/In vivo | NA |
Cell Line | NA |
Inhibition Concentartion | NA |
In vivo Model | NA |
Assay | NA |
Lethal Dose | NA |
Combination Therapy | NA |
Pubmed ID | 12747950 |
Year of Publication | 2003 |
3-D Structure | View in Jmol or Download Structure |