Browse result page of ImmunoSPdb

The total number entries retrieved from this search are 154
IDNameSequenceLengthChiralityN-Terminal ModificationC-Terminal ModificationChemical ModificationLinear/CyclicNatureSourceTargetMechanism of ActionIn vivo/ In vitroCell LineIC-50In vivo ModelAssay TypeLethal DoseCombination TherapyPubmed IDYear of Publication
1204A4HS1II-Sta-Sta-YVPL8LNoneNoneSta = StatineCyclicSyntheticNALymphocytes, MacrophagesInfluence of phagocytic function of macrophages, and the retarding effect of the proliferation of LymphocytesBothSpleen LymphocyteNABALB / C miceDelayed-type hypersensitivity (DTH) test, Lymphocyte Proliferation test, MTTNACN 101289497 A2008
1212SEQ ID NO: 1ILAKFLHWL9LNoneNoneInventors midified C- or at the N-terminus of the peptides with stabilizing groups, groups for increasing the water solubility, luminescent markers, fluorescent markers, radioactive markers, metal markers, polymeric markers, antibodies, enzymes, epitope tags, amino acid, D- or L-amino acids, serine, glycine, aspartate, sugar groups, glucuronic acid, sulfate moieties and polyethylene glycol. for experimentsLinearProtein Derivedhuman telomerase reverse transcriptaseProteasomeInhibits the overall activity of the proteasomeIn vitroHeLa, SaosNANANANADE 102006025146 A12007
1224SEQ ID NO:60LVCYYTSWS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1225SEQ ID NO:61FLCTHIIYS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1226SEQ ID NO:62IIYSFANIS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1227SEQ ID NO:63LKTLLSVGG9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1228SEQ ID NO:64FIKSVPPFL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1229SEQ ID NO:65FDGLDLAWL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1230SEQ ID NO:66LYPGRRDKQ9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1231SEQ ID NO:67YDIAKISQH9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1232SEQ ID NO:68LDFISIMTY9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1233SEQ ID NO:69FISIMTYDF9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1234SEQ ID NO:70FRGQEDASP9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1235SEQ ID NO:71YAVGYMLRL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1236SEQ ID NO:72MLRLGAPAS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1237SEQ ID NO:73LAYYEICDF9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1238SEQ ID NO:74LRGATVHRT9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1239SEQ ID NO:75YLKDRQLAG9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1240SEQ ID NO:76LAGAMVWAL9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1241SEQ ID NO:77VWALDLDDF9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1242SEQ ID NO:78LDLDDFQGS9LNoneNoneNoneLinearProtein DerivedHuman Cartilage glycoprotein 39T-cellsInduce systemic immunological tolerance to the autoantigens under attack of the autoreactive T-cells, specific effect on the autoreactive T cells thus leaving the other components of the immune system intactIn vitroPBMCNANAPeptide HLA-DR binding assay and Proliferative responses of blood mononuclear cells by thymidine incorporation assayNANAWO 1997040068 A11997
1347Formula 9[RKD-NH-CH2]26LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1348Formula 10RKD-NH-CH2-CH2-NH-DKR6LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1349Formula 11[RKDV-NH-CH2]28LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1350Formula 12[RLDV-NH-CH2]28LNoneNoneNoneLinearSyntheticNASuppress the antigen presentation of macrophages or antigen recognition of T-cells in the immune processesInhibit maturation of the T-cell dependent antibody producing cells, supress the phagocytosis and dminish the late hypersensitive responseIn vitroSplenocyte s obtained from ratsNATwelve Wistar (LATI) ratsHummoral Immune Response assayNANAUS 50933201992
1373A2.101-108CDVGSDWR8LNoneNoneNoneLinearProtein Derivedα2 domain of HLA-A2B-Lymphoblastoid cells (B-cell)Inhibit by binding to variable T cell receptorIn vitroJY cells (HKA-A2, B7, DR4,6)NANoneHummoral Immune Response assayNANAUS 58885121999
1438SEQ ID10rlllrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1439SEQ ID11rvllrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1440SEQ ID12rillrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1441SEQ ID13rlvlrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1442SEQ ID14rlilrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1443SEQ ID15rllvrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1444SEQ ID16rllirlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1445SEQ ID17rlllrvllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1446SEQ ID18rlllrillgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1447SEQ ID19rlllrlvlgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1448SEQ ID20rlllrlilgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1449SEQ ID21rlllrllvgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1450SEQ ID22rlllrlligy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1451SEQ ID23rwllrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1452SEQ ID24rlwlrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1453SEQ ID25rllwrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1454SEQ ID26rlllrwllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1455SEQ ID27rlllrlwlgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1456SEQ ID28rlllrllwgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1457SEQ ID29ryllrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1458SEQ ID30rlylrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1459SEQ ID31rllyrlllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1460SEQ ID32rlllryllgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004
1461SEQ ID33rlllrlylgy10DAcetylationAmidationNoneLinearProtein Derived(HLA-B) α1-domainNAInhibited T-cell proliferation, various inflammatory cytokines production.BothRAW264.7 macrophages cellsNACBA miceEnzyme-linked immunosorbent assay (ELISA)NALPSUS 6696545 B12004