GDPbio: Genome based prediction of Diseases and Personal medicines using Bioinformatics

G.P.S. Raghava | Department of Computational Biology | IMTECH | CRDD | Team Members | Contact | FAQ
Concept of GDPbio
 About GDPbio
 Diseases prediction
 Personal Drugs

Diseases and Genes
 Useful Databases
 Diseases Susceptiblity
 Diseases Diagnosis
 Diseases Management
 Diseases Screening

Personal Genomes
 Sequencing Projects
 Genomic Databases
 Problems faced

Personalized Medicines
 Wiki Pages
 Important Links
 Slides (PPT/PDF)

Challenges During Personalized Medicines Development

Below are given some challenges that comes in the personalized medicines development way:
  1. Complexity of Human Genome
  2. Occurence of changes in gene products after translation e.g., post translational modifications etc.
  3. Occurence of polygenic diseases rather than monogenic
  4. Effect of environmental factors upon the phenotype and lack of clinically available data
  5. Convincement of Pharma Industry related problems
  6. Lack of standards for personalized medicines development
  7. Ethical issues