Details of CPPsite entry with Sequence rrrrrrrrGC |
Primary information | |
---|---|
PEPTIDE SEQUENCE | rrrrrrrrGC |
CPPsite ID | 2672, |
PEPTIDE NAME | r8 |
CHIRALITY | D |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
CATEGORY | Cationic |
C-TERMINAL MODIFICATION | Amidation |
UPTAKE EFFICIENCY | Marked accumulation of r8 was observed in the tumor xenografts, 3 times more than L form and nine times higher than that of the control GC peptide |
INVITRO/INVIVO | In vivo |
In VIVO MODEL | Tumor-xenografted nude mice |
CARGO | Fluorophore (Alexa660), Small molecule drug (doxorubicin) |
PMID | 22285548 |
PATENT | Unknown |
Tertiary Structure (Technique) | 2672 (PEPstrMOD), |