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Details of CPPsite entry with Sequence rrrqrrkkr
Primary information
PEPTIDE SEQUENCErrrqrrkkr
CPPsite ID 1013, 1204,
PEPTIDE NAMED-Tat (57-49), Tat (57-49)
CHIRALITYD, D
LINEAR/CYCLICLinear, Linear
SOURCEProtein derived, Protein derived
CATEGORYCationic, Cationic
SUB CELLULAR LOCALIZATIONProbably cytoplasm and nucleus, nucleolus, Vesicles
N-TERMINAL MODIFICATIONConjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer, Conjugation with K-FITC
C-TERMINAL MODIFICATIONFree, Free
CHEMICAL MODIFICATIONNA, NA
UPTAKE EFFICIENCYHigh (greater than Tat (49-57)), Lower than CyLoP1
PROPOSED UPTAKE MECHANISMProbably non-endocytic pathway, Probably endocytic process
INVITRO/INVIVOIn vitro, In vitro
CELL LINEJurkat, NIH-3T3
In VIVO MODELNA, NA
CARGOFluorophore (fluorescein), Fluorophore (FITC)
PMID11087855, 21319732
PATENTUS 6593292, Unknown
Tertiary Structure
(Technique)		1013 (PEPstrMOD), 1204 (PEPstrMOD),