Welcome to Entry Card of Peptide


This page gives details of CPPsite entry with ID 1013
Primary information
CPPsite ID1013
PEPTIDE SEQUENCErrrqrrkkr
PEPTIDE NAMED-Tat (57-49)
CHIRALITYD
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYCationic
SUB CELLULAR LOCALIZATIONProbably cytoplasm and nucleus, nucleolus
N-TERMINAL MODIFICATIONConjugation with fluorescein with 6-aminohexanoic acid (Ahx) spacer
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYHigh (greater than Tat (49-57))
PROPOSED UPTAKE MECHANISMProbably non-endocytic pathway
INVITRO/INVIVOIn vitro
CELL LINEJurkat
CARGOFluorophore (fluorescein)
PMID11087855
PATENTUS 6593292
LENGTH9
Secondary StructureCTTHHHHCC
SMILESN[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCC(=O)N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCNC(=[NH2])N)C(=O)N[C@H](CCCC[NH3])C(=O)N[C@H](CCCC[NH3])C(=O)N[C@H](CCCNC(=[NH2])N)C=O
Tertiary Structure
(Technique)		View in Jmol  OR Download Structure
  (PEPstrMOD)