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Details of CPPsite entry with Sequence WEARLARALARALARHLARALARALRACEA
Primary information
PEPTIDE SEQUENCEWEARLARALARALARHLARALARALRACEA
CPPsite ID 2469,
PEPTIDE NAMERALA
CHIRALITYL
LINEAR/CYCLICLinear
SOURCESynthetic
CATEGORYCationic and amphipathic
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONFree
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYRALA/pDNA nanoparticles in vitro is comparable with commercial transfecting agents while exhibiting significantly lower cytotoxicity
PROPOSED UPTAKE MECHANISMEndocytic pathway
INVITRO/INVIVOIn vitro and in vivo
CELL LINEZR-75-1, PC-3 and NCTC-929
In VIVO MODELFemale C57BL/6 mice
CARGONanoparticle (Cy3-labeled nanoparticles complexed with DNA)
PMID24995949
PATENTUnknown
Tertiary Structure
(Technique)		2469 (PEPstrMOD),