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Details of CPPsite entry with Sequence VKRGLKLRHVRPRVTRMDV
Primary information
PEPTIDE SEQUENCEVKRGLKLRHVRPRVTRMDV
CPPsite ID 1212,
PEPTIDE NAMEDPV1047
CHIRALITYL
LINEAR/CYCLICLinear
SOURCEProtein derived
CATEGORYUnknown
SUB CELLULAR LOCALIZATIONNucleus
N-TERMINAL MODIFICATIONCys addition
C-TERMINAL MODIFICATIONFree
UPTAKE EFFICIENCYLower than other DPVs and tat (48-60)
PROPOSED UPTAKE MECHANISMEnergy-dependent caveolar endocytic independent mechanism
INVITRO/INVIVOIn vitro
CELL LINEHeLa, HCT116, HL-60, K562, Molt4, NIH-3T3 and primary hepatocyte cultures
CARGOProtein (PO and IgG)
PMID15859953
PATENTUnknown
Tertiary Structure
(Technique)
1212 (PEPstrMOD),