Details of CPPsite entry with Sequence VKRGLKLRHVRPRVTRMDV |
Primary information | |
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PEPTIDE SEQUENCE | VKRGLKLRHVRPRVTRMDV |
CPPsite ID | 1212, |
PEPTIDE NAME | DPV1047 |
CHIRALITY | L |
LINEAR/CYCLIC | Linear |
SOURCE | Protein derived |
CATEGORY | Unknown |
SUB CELLULAR LOCALIZATION | Nucleus |
N-TERMINAL MODIFICATION | Cys addition |
C-TERMINAL MODIFICATION | Free |
UPTAKE EFFICIENCY | Lower than other DPVs and tat (48-60) |
PROPOSED UPTAKE MECHANISM | Energy-dependent caveolar endocytic independent mechanism |
INVITRO/INVIVO | In vitro |
CELL LINE | HeLa, HCT116, HL-60, K562, Molt4, NIH-3T3 and primary hepatocyte cultures |
CARGO | Protein (PO and IgG) |
PMID | 15859953 |
PATENT | Unknown |
Tertiary Structure (Technique) | 1212 (PEPstrMOD), |