Details of CPPsite entry with Sequence RXRRBRRXRYQFLIRXRBRXRB |
Primary information | |
---|---|
PEPTIDE SEQUENCE | RXRRBRRXRYQFLIRXRBRXRB |
CPPsite ID | 2315, |
PEPTIDE NAME | Pip6a |
CHIRALITY | Modified |
LINEAR/CYCLIC | Linear |
SOURCE | Synthetic |
SUB CELLULAR LOCALIZATION | Vesicles |
N-TERMINAL MODIFICATION | Acetylation |
C-TERMINAL MODIFICATION | Free |
CHEMICAL MODIFICATION | B, Beta-Alanine and X, 6-aminohexanoic acid (Ahx) |
UPTAKE EFFICIENCY | Dose dependent uptake |
PROPOSED UPTAKE MECHANISM | Energy and caveolae-mediated endocytosis |
INVITRO/INVIVO | In vitro and in vivo |
CELL LINE | Murine H2k mdx myoblasts and C2C12 cells |
In VIVO MODEL | 1- to 2-day-old newborn wild-type C57BL/6 J mice |
CARGO | Nucleic acid [phosphorodiamidate morpholino oligomers (PMO)] |
PMID | 24366877 |
PATENT | Unknown |
Tertiary Structure (Technique) | Not Predicted), |