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This page gives details of CPPsite entry with ID 2315
Primary information
CPPsite ID2315
PEPTIDE SEQUENCERXRRBRRXRYQFLIRXRBRXRB
PEPTIDE NAMEPip6a
CHIRALITYModified
LINEAR/CYCLICLinear
SOURCESynthetic
SUB CELLULAR LOCALIZATIONVesicles
N-TERMINAL MODIFICATIONAcetylation
C-TERMINAL MODIFICATIONFree
CHEMICAL MODIFICATIONB, Beta-Alanine and X, 6-aminohexanoic acid (Ahx)
UPTAKE EFFICIENCYDose dependent uptake
PROPOSED UPTAKE MECHANISMEnergy and caveolae-mediated endocytosis
INVITRO/INVIVOIn vitro and in vivo
CELL LINEMurine H2k mdx myoblasts and C2C12 cells
In VIVO MODEL1- to 2-day-old newborn wild-type C57BL/6 J mice
CARGONucleic acid [phosphorodiamidate morpholino oligomers (PMO)]
PMID24366877
PATENTUnknown
LENGTH22
Secondary StructureNA
SMILESNA
3-D StructureNot Predicted